Fda Cautions Against Use Of Hydroxychloroquine Or Chloroquine For Covid

These drugs are vulnerable bases, and they concentrate in the acid food vacuole of the parasite. Chloroquine intercalates DNA, but only at concentrations much higher (1-2 μM) than necessary to wipe out malaria parasites (10-20 nM). Chloroquine binds to ferriprotoporphyrin IX, a product of haemoglobin degradation, and in that way chemically inhibits haem dimerization. Inhibition… Continue reading Fda Cautions Against Use Of Hydroxychloroquine Or Chloroquine For Covid